General Information:

Date of Birth: 14 / DEC / 1975

Place of Birth: Zlin, Czech Republic

Place of Abode: Slavicin and Sobotovice, Czech Repubic



Masaryk University, School of Medicine, Brno, Czech Republic, 1994—2001. Degree: M.D.

 WWW: ( Masaryk University Brno) / ( School of Medicine, MU Brno)


Professional Experience and Training:

2004-to present: Physician, Masaryk Memorial Cancer

   Institute, Dpt. of Comprehensive Cancer Care, Brno, CZ 

   Head: Assoc. Prof. R. Vyzula, M.D., Ph.D.

    WWW: ( Masaryk Memorial Cancer Institute)

2002-2004: Physician, University Hospital Brno, Dpt. of

   Internal Medicine - Haematooncology, Brno, CZ

   Head: Prof. J. Vorlicek, M.D.,Ph.D., WWW: ( IHOK FN BRNO )

2001-2002: Research Associate in Medicine, Harvard Medical

   School, Harvard University, Boston, USA


   Research Associate, Department of Adult Oncology, 

   Dana - Farber Cancer Institute, Boston, USA

   Head of Laboratory: Assoc. Prof. A.S. Freedman, M.D.

    WWW: (Dana-Farber Cancer Institute, Boston) / (Harvard Medical School, Boston)


2003: European Bioinformatics Institute - European Molecular

   Biology Laboratory, Hinxton, Cambridge, UK WWW:( EMBO)

2000: Dana - Farber Cancer Institute, Boston, USA

2000: Institute of Hematology and Blood Transfusion, Molecular

   Genetics Laboratory, Prague, CZ    WWW:( IHBT / UHKT)

2000: Laboratory of Experimental Medicine,University of Palacky,

   Olomouc, CZ   WWW: ( Palacky University Olomouc)


1) Astier, A.L., Svoboda, M., Hinds, E., et al.: Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation. Leukemia. 2004 Apr;18(4):873-5.

2) Svoboda, M., Michálek,J.: Úvod do technologie DNA čipů (The Introduction to DNA chips´technology). Lékař a technika (In Czech), 2004, 35(3): 67-75.

3) Michálek, J., Svoboda, M.: Buněčná imunoterapie nádorů (Cellular immunotheraphy of cancer). Klinická onkologie (in Czech),  2003, 16(3):145-148.

4) Astier, A.*, Ronghui, X.*, Svoboda, M.**, et al.: Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor. Identification of pathways regulating B cells survival. Blood, 2003, 101: 1118-1127. * the 1st author, ** the 2nd author  

 5) Sarkar, S., Svoboda, M., de Beaumont, R., et al.: The role of AKT and   RAFTK in beta1 integrin mediated Survival of precursor B-acute lymphoblastic    leukemia cells. Leukemia and Lymphoma, 2002, 43(8): 1663-1671.   

 6) Sarkar, S., Svoboda, M., Freedman, A.S., Activation of AKT following beta1      integrin ligation modulates survival of B - acute lymphoblastic leukemia cells.     Blood, 2000, 96(11): 349 -( abstract )


1) 2003-2004: Principal Investigator - grant of Fond rozvoje vysokých škol, MŠMT (Ministry of Education), No.: 464/2003

2) 2001-2002: Research Fellow, grant of National Institutes of Health (NIH), USA, No.: CA06516

3) 2000-2002: Research Fellow, grant of NIH, USA, No.:CA81494

Academic Achievements:

Member of Czech Society of Oncology, (www: COS)

Member of the Council of the Dean of School of Medicine, Masaryk 

      University Brno (MU), 1998-1999, 2003 - to present                    

Member of Academic Senate of School of Medicine, MU, 2003-to 


Member of Moravian Oncological Foundation, Since 1998 

Member and Vice-chairman of Academic Senate of MU, 1996-1998

Member of Red Cross, Since 1987 

 Dean' s Prize, School of  Medicine, MU,  2000 

Health Care Press Prize, January 1999

 Holder of stipend of Dagmar and Vaclav Havel Foundation—VIZE 97,

      2001. (www: Vize 97 Foundation)

Holder of Jan Pivecka Foundation´s stipend , 2000 - 2001

      (www: Jan Pivecka Foundation)

 Holder of J., M. and Z. Hlavkovych Foundation’s stipend, 2000.


Profesional Interests:

          Oncology, Molecular Biology and Genetics, DNA microarrays, 

          Predictive Oncology

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